diff --git a/CHANGELOG.md b/CHANGELOG.md
index dba1c500d..b9d727a9b 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -9,6 +9,9 @@ and this project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0
 
 ### Added
 
+- `TwilioFrameSerializer` can now specify Twilio's and Pipecat's desired sample
+  rates to use.
+
 - Added new `on_participant_updated` event to `DailyTransport`.
 
 - Added `DailyRESTHelper.delete_room_by_name()`.
diff --git a/src/pipecat/serializers/twilio.py b/src/pipecat/serializers/twilio.py
index 713f43a86..8836fcd6d 100644
--- a/src/pipecat/serializers/twilio.py
+++ b/src/pipecat/serializers/twilio.py
@@ -7,18 +7,25 @@
 import base64
 import json
 
+from pydantic import BaseModel
+
 from pipecat.frames.frames import AudioRawFrame, Frame
 from pipecat.serializers.base_serializer import FrameSerializer
-from pipecat.utils.audio import ulaw_8000_to_pcm_16000, pcm_16000_to_ulaw_8000
+from pipecat.utils.audio import ulaw_to_pcm, pcm_to_ulaw
 
 
 class TwilioFrameSerializer(FrameSerializer):
+    class InputParams(BaseModel):
+        twilio_sample_rate: int = 8000
+        sample_rate: int = 16000
+
     SERIALIZABLE_TYPES = {
         AudioRawFrame: "audio",
     }
 
-    def __init__(self, stream_sid: str):
+    def __init__(self, stream_sid: str, params: InputParams = InputParams()):
         self._stream_sid = stream_sid
+        self._params = params
 
     def serialize(self, frame: Frame) -> str | bytes | None:
         if not isinstance(frame, AudioRawFrame):
@@ -26,7 +33,7 @@ class TwilioFrameSerializer(FrameSerializer):
 
         data = frame.audio
 
-        serialized_data = pcm_16000_to_ulaw_8000(data)
+        serialized_data = pcm_to_ulaw(data, frame.sample_rate, self._params.twilio_sample_rate)
         payload = base64.b64encode(serialized_data).decode("utf-8")
         answer = {
             "event": "media",
@@ -47,6 +54,12 @@ class TwilioFrameSerializer(FrameSerializer):
             payload_base64 = message["media"]["payload"]
             payload = base64.b64decode(payload_base64)
 
-            deserialized_data = ulaw_8000_to_pcm_16000(payload)
-            audio_frame = AudioRawFrame(audio=deserialized_data, num_channels=1, sample_rate=16000)
+            deserialized_data = ulaw_to_pcm(
+                payload,
+                self._params.twilio_sample_rate,
+                self._params.sample_rate)
+            audio_frame = AudioRawFrame(
+                audio=deserialized_data,
+                num_channels=1,
+                sample_rate=self._params.sample_rate)
             return audio_frame
diff --git a/src/pipecat/utils/audio.py b/src/pipecat/utils/audio.py
index a3fc1b0ab..0764c6abb 100644
--- a/src/pipecat/utils/audio.py
+++ b/src/pipecat/utils/audio.py
@@ -34,21 +34,21 @@ def exp_smoothing(value: float, prev_value: float, factor: float) -> float:
     return prev_value + factor * (value - prev_value)
 
 
-def ulaw_8000_to_pcm_16000(ulaw_8000_bytes):
+def ulaw_to_pcm(ulaw_bytes: bytes, in_sample_rate: int, out_sample_rate: int):
     # Convert μ-law to PCM
-    pcm_8000_bytes = audioop.ulaw2lin(ulaw_8000_bytes, 2)
+    in_pcm_bytes = audioop.ulaw2lin(ulaw_bytes, 2)
 
-    # Resample from 8000 Hz to 16000 Hz
-    pcm_16000_bytes = audioop.ratecv(pcm_8000_bytes, 2, 1, 8000, 16000, None)[0]
+    # Resample
+    out_pcm_bytes = audioop.ratecv(in_pcm_bytes, 2, 1, in_sample_rate, out_sample_rate, None)[0]
 
-    return pcm_16000_bytes
+    return out_pcm_bytes
 
 
-def pcm_16000_to_ulaw_8000(pcm_16000_bytes):
-    # Resample from 16000 Hz to 8000 Hz
-    pcm_8000_bytes = audioop.ratecv(pcm_16000_bytes, 2, 1, 16000, 8000, None)[0]
+def pcm_to_ulaw(pcm_bytes: bytes, in_sample_rate: int, out_sample_rate: int):
+    # Resample
+    in_pcm_bytes = audioop.ratecv(pcm_bytes, 2, 1, in_sample_rate, out_sample_rate, None)[0]
 
     # Convert PCM to μ-law
-    ulaw_8000_bytes = audioop.lin2ulaw(pcm_8000_bytes, 2)
+    ulaw_bytes = audioop.lin2ulaw(in_pcm_bytes, 2)
 
-    return ulaw_8000_bytes
+    return ulaw_bytes